I’m all for natural media emulation from 3D scenes. So I was pleased to see the new $15 Pencil Pro add-on for Blender, allowing your 3D scene to emulate a pencil drawing. The result is obviously not great at long distance (e.g. a city scene), where it looks like a point-cloud with the points mapped to tiny graphite strokes. Better for medium and close animation shots, though there’s still a distinct Rhubarb & Custard-style wobble. Which is charmingly old-school in its way, and would be acceptable to young kids watching shorts.
Suitably rough and sketchy and believable, if you overlook the polygonal angles from the 3D. No per-frame autocolour, but something that auto-colours greyscale (e.g. Akvis Coloriage AI) might give colourisation that is not too wobbly, when run frame by frame.